The V600 is lucky to actually resolve 2200 to 2400 ppi. With that, I would set to 3200 and leave it there. With a high Rez scanner, you can benefit from more. For example, scanning fine grain films and comparing 4000 ppi with 6300 for example on an Imacon, looking at a 16x24 or larger print, there is a bit more detail and a natural look in comparison. The grain looks better. Splitting hairs really. For 35mm, the new Plusteks released the last few years are pretty decent and will surpass your V600