Think Tank Streetwalker Hard Drive backpack, it simply doesn't get any better than this for full featured photo backpacks. I looked at every brand available before buying this one and it simply outclassed all the competition. I bought this for flying with a full Nikon system, including a pair of D4's, 14-24, 24-70, and 70-200 2.8 lenses, plus speedlights, a 15" laptop and lots of accessories. It carried all of that with ease, but the pack itself is still slim, lightweight, and carry-on legal for all flights. I used this exactly twice and it is like new in every way. I have since downsized my travel kit to mirrorless gear and I don't need a backpack of this size.
Includes the rain cover and tripod straps. Case is rugged, built to protect your gear and last. Asking $150
StreetWalker® HardDrive V2.0
Think Tank Photo Backpack