<p>After years of not scanning I just scanned a couple of rolls of slide film with my Nikon LS-5000. I'm using Nikonscan as the last time I used Vuescan it has errors which I reported to Ed H. and then gave up on the program. I spent way too much time testing and debugging that software a decade ago. I recommend disabling/not using most of its software correction settings as I found them worse than useless (agree with Ty's post above. Set white/black clipping to 0%, film type to generic, color balance none and fix the color in Photoshop).<br /><br />Anyway, on my slides I see similar issues at black edges (edge of the frame as well as bright areas with shadows immediately adjacent.) I also notice pepper grain on Provia slides in smooth highlights. I figured out I can minimize pepper grain (at the slight expense of detail) by changing the cleaning from normal to fine. <br /><br />For the ghosting, the best advice I have is not to overbrighten shadows, as this exposes the scanner's flaws. From pepper grain to soft corners to scanner noise to flare/ghosting, scanning is a lossy procedure. I have resigned myself to minimizing problems through good technique but making peace with the limitations of scanning itself.</p>