Blister beetles are beetles (Coleoptera) of the family Meloidae, so called for their defensive...

Toxicity

The blister beetle genus Epicauta is highly toxic to horses. A few

beetles consumed in a single feeding of alfalfa hay may be lethal.

Poisonings have also been reported after use of "Spanish fly"-type folk

medicines, and after handling blister beetle individuals. The toxic

chemical is cantharidin.

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