I'd really like to see someone develop a matrix or chart of sorts, indicating which Canon body will work with what application (Lightroom, Capture One, Aperture, EOS Utility, etc) and on what OS version. And there are many OS versions, when you think about it. Upgrade your OS and your tethered connection quits. Invest in a different application and your tethered connection quits. Keep your older Canon DSLR and your tethered connection quits. Example: A Canon 5D does NOT work with Capture One on OS X Lion (10.7.) It DOES work with Capture One on OS X 10.6.8. Is anyone familiar with a matrix like this? Or does anyone care to share their experiences and maybe I could create (and share) this chart? Thanks!