Like David T. I have gone through Ian Lyons nicely written tutorial and several references but am confused as what is causing the difference in output. Background: I'm printing off of a Mac G5 running the latest version of Leopard using Photoshop CS3 with a recently calibrated LCD monitor using Spyder2. All of my epson drivers are up to date and I worked my way through the craziness of Apple trying to be helpful with their print drivers as a default. I'm printing from an epson r1800 nozzle check shows all cartridges are firing correctly. When I print using Photoshop manages colors using say Spr 1800 EnhMatte BstPhto.icc the output is very close to the LCD monitor except it is slightly darker. When I print using Printer Manages colors (see settings) the output is just about dead on and good enough to work from. Questions: 1. Any idea what is causing the difference in output? Clearly I should stay with Printer manages color. But Ian Lyons says, "This option produces by far the best print quality." but doesn't explain why. From my perspective the best print quality doesn't help me unless it matches my monitor as closely as possible. Where this darkness is problematic is in subtle shadow detail. I am aware that on an LCD shadows will show my more detail than a reflected light print but when I use "photoshop manages colors" subtle shadow detail is typically lost but "Printer manages colors" maintains this detail on printed output. 2. In the printer dialog box there is a high speed option. I've tested it both ways and can not perceive a difference. Do you typically leave this checked too or do you see a difference? Could be me or my printer since every printer is slightly different. 3. I'm guessing a way to resolve this issue is to get a custom profile of my paper/ink combo (yes I'm using real epson inks). Have you gone this route and did it resolve your printer/monitor differences? Thanks in advance for any suggestions or insights.