After a few years spent shooting digital, I'm going back to film - I just seem to enjoy the simplicity of the shooting process and a certain ineffable quality of the final product. For 35mm, I seem to have found a satisfactory workflow: I have my c41 negatives processed by a lab and do my own scanning with my old Minolta Scan Dual III film scanner + Vuescan + Colourperfect plugin. The results are, to me, nothing short of amazing and I have no complaints about the procedure. I am just starting to explore medium format and this brings me to my question. Ideally I'd like to come up with a medium format workflow that resembles the one I use for 35mm. This is, however, not feasible at the moment, as the expense to buy a dedicated medium format film scanner is too high (this includes dodgy used Nikon 8000s/9000s on ebay). I resorted to purchasing an Epson V550, which I believe is an updated V600 with minor differences. I set it up and tested it yesterday, with a few 6x4.5 Ektar 100 negatives shot on a Fuji GA645i. On the positive side, my results *far* exceed the poor quality low-res scan that came from the lab together with the developed negatives. It is shocking how poor the jpeg scan from the "professional" lab were - and I thought the culprit was the camera or film or both! On a negative note, I think I'm still not completely satisfied with the V550's output. Using the standard Epson MF film holder, the scanner clearly does not resolve the grain. I can tell that because, while on my 35mm scans from the Minolta Scan Dual even the particles of dust on the negatives are sharp and in focus, on my V550 MF output the dust is blurry and soft. I have tried placing the negative directly on the scanner glass and rescanning in Vuescan: I see no difference in sharpness w.r.t using the Epson holder to scan. I have read that the V550/V600 models have a fixed optics with relatively high depth of field, compared to the better models (V700/V800) which have tighter DOF but allow for higher focus plane fine tuning. Can people confirm this? If this is true, then I'm suspecting that the (poor) sharpness I see is all I'm ever going to get with this scanner? Else, have people used after-market film holders (betterscanning? Lomography DigitaLIZA?) and seen sharpness improvements with this scanner on MF material?