Is there any option of true binning in the super high MP cameras? I'll explain. I use in my work (microscopy) low resolution, extremity high sensitivity, cameras. They have a pixel size of about 6x6u (microns) or even 13x13u. So they can literally see 10s of photons and still get a signal. Now, to gain even higher sensitivity, at the cost of resolution, we can "bin". This means, we can combine pixels to act as a single pixel. For example, if my native res is 600x400, and I bin at 2x2, I have an actual resolution of 300x200, but now, I have 4 pixels gathering light and feeding into a single point. I was wondering if any Nikon cameras can do that. As far as I understand, increasing ISO, does not, of course, increase the size of a pixel (unlike in the old film, where you get a physically larger grain), rather higher ISO increases the voltage to multiply the signal from less photons, hence noise, because you are using the electronic conversion process itself to create a stronger signal. However, in a 24MP camera, I would like to be able to set it at say 12MP, so although I will get lower resolution, I now have much larger pixels and hence better light sensitivity. So I do not need to use a higher ISO, larger apurture or slower speed, to gain better sensitivity/ exposure.