<p>I had the same situation: I had upgraded to Win10 and used my Spyder3 there. It worked, did calibrations etc., but I had the impression that something was wrong. So I contacted Datacolor and in the end I bought a Spyder5 with 30% discount and I even got a lenscal with it. And it gave me much better results. Comparing the two profiles, Spyder3 had cut me a lot of greens compared to sRGB and the Spyder5 profile was much better.<br>
This is what Datacolor wrote in their answer:<br>
"we tested Spyder3 on a few Windows 10 machines, however, depending upon your computer's configuration, the software may run or not run. In order to find this out, you may check it on your computer.<br>
We recommend to upgrade to the new Spyder5 with it’s up to 55% Improvement in Low Luminance Accuracy vs. Spyder4 sensors, the interactive Help, the new industrial design including a lens cap for sensor protection, the enhanced SpyderProof functionality, the multiple monitor support for Spyder5EXPRESS, PRO and ELITE and it’s double shielded filters for higher durability and greater longevity. This gives you the ability to show your clients, friends and family calibrated images anywhere."</p>